SuppSafety is informational only and not medical advice. Read the disclaimer.

Iron

Also known as: Ferrous sulfate, Ferrous bisglycinate

Moderate evidenceMineralSource-reviewedModerate cautionEnergy & FocusGeneral Wellness

Iron supports normal red-blood-cell function. It is commonly used when testing shows low iron. Taking iron without a need is discouraged because excess can be harmful. Talk to a professional and consider testing first.

Not medical advice. SuppSafety and StackWise are informational only. Talk to a qualified healthcare professional before starting, stopping, or combining supplements.

Snapshot

Evidence levelModerate evidence
Caution levelModerate caution
Source reviewSource-reviewed
Last reviewed2026-07-02

What this page can tell you: Commonly discussed timing, food notes, caution categories, and an honest note on how much source review this entry still needs.

What it cannot: Whether this is appropriate for you personally, or that it treats, prevents, or cures any condition. Informational only — discuss with a clinician or pharmacist.

🕒 Timing

When: Morning

Food: Empty stomach

Sometimes taken on an empty stomach for absorption, or with food if it upsets the stomach. Vitamin C may help absorption; separate from calcium.

💊 Common use range

Varies — professional-guided mg elemental

Iron can be toxic in excess, especially for children. Use only with professional guidance and keep away from children.

Ranges are informational, not a recommended dose. Talk to a professional about what is right for you.

🤔 Worth considering?

Evidence vs. effort: Strong evidence relative to burden

Clearly useful for correcting a demonstrated deficiency, and iron status can be measured. Supplementing without a known need is commonly discouraged, can upset the stomach, and acute overdose is dangerous, especially for children. Worth confirming a need with a professional first.

A general summary, not a recommendation. Whether something fits your situation is worth discussing with a healthcare professional.

⚠️ Commonly noted interactions (supplements)

Often about absorption or timing rather than danger — separating doses is common. This list is not exhaustive.

🧭 Caution level

Moderate caution
  • Mineral spacing considerations
  • Narrow margin — easy to exceed the upper limit at higher doses
  • Higher caution if you take certain antibiotics (space doses apart)
  • Higher caution if you take thyroid medication (space doses apart)

Caution level is an informational summary of commonly discussed caution categories and doses — not a safety rating, approval, or medical advice. Low caution does not mean safe for you.

🩺 Medication caution categories

  • Certain antibiotics
  • Thyroid medication

🏥 Surgery & procedure caution

Share iron use with your care team; iron status is relevant around surgery.

If you have a procedure scheduled, bring your full supplement list to your surgical and anesthesia team. Do not stop prescribed medication unless your clinician tells you to. Do not start or stop supplements based only on this app.

✅ Quality checklist

  • Prefer products with third-party testing or a certificate of analysis (COA).
  • Check the label for the exact form and the elemental or active amount per serving.

🧩 Commonly paired with

🔁 Alternatives

None listed.

🗣️ Questions for a professional

  • Is Iron appropriate alongside my medications and health history?
  • Is there a test or check that would tell us whether I actually need it?

🔬 Evidence snapshot

An essential mineral and a component of hemoglobin that carries oxygen in the blood. Supplementation is used to correct or prevent iron deficiency; routine high-dose use without a known deficiency is not supported and can cause harm.

🧪 Forms & quality

Needs evidence review — no source-reviewed information yet. We only show dose and monitoring details after they have been checked against reputable sources.

See the supplement glossary for what form names like "L-", chelated, or standardized extract mean.

📏 Dose & monitoring

NIH ODS sets an adult (19+) Tolerable Upper Intake Level of 45 mg/day.

Evidence vs. burden: Strong evidence relative to burden

Labs that may be worth discussing: Iron status

Iron status can be measured; supplementing without a known need is commonly discouraged. This may be worth discussing with a healthcare professional.

These are discussion prompts, not required tests. A healthcare professional can advise what makes sense for you.

😐 Commonly reported side effects

  • Constipation, nausea, dark stools; toxic in overdose

Non-exhaustive and individual.

🔄 Cycling & breaks

Use is commonly guided by testing rather than fixed cycles.

📅 Daily use notes

Only supplement iron when a need is identified. Separate from calcium, zinc, and magnesium.

📋 Source review status

Source-reviewed — last reviewed 2026-07-02

Placeholder — reinforce test-first and child-safety messaging.

📚 References

Verified against the source shown. See the research-status page for how review works.

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Not medical advice. SuppSafety and StackWise are informational research and tracking tools. They are not medical advice and do not diagnose, treat, cure, or prevent any condition. Supplement research is often limited or mixed, and individual needs vary. Always talk to a qualified healthcare professional before starting, stopping, or combining supplements — especially if you take medication, have a health condition, are pregnant or breastfeeding, or have a procedure scheduled.