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Lion's Mane Mushroom

Also known as: Hericium erinaceus

Preliminary evidenceFunctional mushroomNeeds evidence reviewModerate cautionBrain & MemoryMood & Stress

Lion's mane is a functional mushroom people commonly explore for cognitive and nerve wellness. Human evidence is preliminary and product quality varies widely. It is not a treatment for any neurological condition.

Not medical advice. SuppSafety and StackWise are informational only. Talk to a qualified healthcare professional before starting, stopping, or combining supplements.

Snapshot

Evidence levelPreliminary evidence
Caution levelModerate caution
Source reviewNeeds evidence review
Last reviewed

What this page can tell you: Commonly discussed timing, food notes, caution categories, and an honest note on how much source review this entry still needs.

What it cannot: Whether this is appropriate for you personally, or that it treats, prevents, or cures any condition. Informational only — discuss with a clinician or pharmacist.

🕒 Timing

When: Morning, With a meal

Food: With or without food

Timing is flexible; commonly taken in the morning.

💊 Common use range

500–1,000 mg extract

Follow product guidance; extracts vary widely in strength.

Ranges are informational, not a recommended dose. Talk to a professional about what is right for you.

⚠️ Commonly noted interactions (supplements)

None listed.

Often about absorption or timing rather than danger — separating doses is common. This list is not exhaustive.

🧭 Caution level

Moderate caution
  • Evidence not fully source-reviewed yet

Caution level is an informational summary of commonly discussed caution categories and doses — not a safety rating, approval, or medical advice. Low caution does not mean safe for you.

🩺 Medication caution categories

None flagged here, but always review your full routine with a professional.

🏥 Surgery & procedure caution

Not a well-established surgical concern; share your supplement list.

If you have a procedure scheduled, bring your full supplement list to your surgical and anesthesia team. Do not stop prescribed medication unless your clinician tells you to. Do not start or stop supplements based only on this app.

✅ Quality checklist

  • Prefer products with third-party testing or a certificate of analysis (COA).
  • Check the label for the exact form and the elemental or active amount per serving.

🔁 Alternatives

🗣️ Questions for a professional

  • Is Lion's Mane Mushroom appropriate alongside my medications and health history?
  • Is there a test or check that would tell us whether I actually need it?

🔬 Evidence snapshot

Overall evidence level here is listed as "Preliminary evidence". A detailed, source-reviewed evidence summary has not been completed yet.

🧪 Forms & quality

Needs evidence review — no source-reviewed information yet. We only show dose and monitoring details after they have been checked against reputable sources.

See the supplement glossary for what form names like "L-", chelated, or standardized extract mean.

📏 Dose & monitoring

Needs evidence review — no source-reviewed information yet. We only show dose and monitoring details after they have been checked against reputable sources.

Evidence vs. burden: Not yet reviewed

😐 Commonly reported side effects

  • Uncommon; possible digestive upset or skin reaction in sensitive people

Non-exhaustive and individual.

🔄 Cycling & breaks

No established cycling pattern.

📅 Daily use notes

People with mushroom allergies should be cautious.

📋 Source review status

Needs evidence review

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Not medical advice. SuppSafety and StackWise are informational research and tracking tools. They are not medical advice and do not diagnose, treat, cure, or prevent any condition. Supplement research is often limited or mixed, and individual needs vary. Always talk to a qualified healthcare professional before starting, stopping, or combining supplements — especially if you take medication, have a health condition, are pregnant or breastfeeding, or have a procedure scheduled.