Manganese
Also known as: Manganese glycinate
Manganese is an essential trace mineral involved in bone formation and several enzyme systems, and it is widely present in foods like whole grains, nuts, legumes, and tea. Most diets supply enough, so routine supplementation is often unnecessary. At the same time, very high chronic intakes have neurological discussions in the literature, which is why staying within commonly cited limits is emphasized rather than taking more.
Snapshot
What this page can tell you: NIH ODS figures for manganese's upper limit, that most diets supply enough, and the lack of known medication interactions.
What it cannot: Whether you need supplemental manganese — most people get enough from food. Informational only.
🧩 Stack insights — how this fits into a schedule
Total daily manganese — NIH ODS sets an adult upper limit of 11 mg/day (all sources); most diets already supply enough, and very high intakes are associated with neurological effects. Check whether a multivitamin already includes it.
Relationship insights are informational only — they describe what is commonly discussed or studied, not what you should take. Not medical advice; review your routine with a clinician or pharmacist.
🧭 How manganese caution scales with the amount
| Amount | Caution level | Note |
|---|---|---|
| Common label amount (~1.8–2.3 mg) | Low–Moderate | Most diets already supply enough; multivitamins often include it. |
| At/above the upper limit (11 mg/day) | High | NIH ODS adult UL; very high intakes have neurological discussions. |
Official figures, not a personal recommendation.
🕒 Timing
When: With a meal
Food: With food
Commonly taken with food; timing is otherwise flexible.
💊 Common use range
1.8–2.3 mg
A commonly cited adult upper limit is around 11 mg/day from all sources — verify this figure; most people already meet needs from food.
Ranges are informational, not a recommended dose. Talk to a professional about what is right for you.
⚠️ Commonly noted interactions (supplements)
None listed.
Often about absorption or timing rather than danger — separating doses is common. This list is not exhaustive.
🧭 Caution level
- Mineral spacing considerations
- Narrow margin — easy to exceed the upper limit at higher doses
Caution level is an informational summary of commonly discussed caution categories and doses — not a safety rating, approval, or medical advice. Low caution does not mean safe for you.
🩺 Medication caution categories
None flagged here, but always review your full routine with a professional.
🏥 Surgery & procedure caution
Not a well-established surgical concern; share your full supplement list with your care team.
If you have a procedure scheduled, bring your full supplement list to your surgical and anesthesia team. Do not stop prescribed medication unless your clinician tells you to. Do not start or stop supplements based only on this app.
✅ Quality checklist
- Prefer products with third-party testing or a certificate of analysis (COA).
- Check the label for the exact form and the elemental or active amount per serving.
🧩 Commonly paired with
🔁 Alternatives
🗣️ Questions for a professional
- Do I have any reason to supplement manganese beyond my normal diet?
🛡️ Safety notes (source-reviewed)
- NIH ODS adult upper limit: 11 mg/day from all sources.
- Very high intakes are associated with neurological effects (tremors, muscle spasms, mood/sleep effects).
- NIH ODS: manganese is not known to interact with any medicines.
⚖️ Evidence limitations
- Routine supplementation is often unnecessary; check your multivitamin first.
❓ Frequently asked
Do I need a manganese supplement?
Most diets supply enough manganese (NIH ODS), and multivitamins often include it. Check your total before adding more; the upper limit is 11 mg/day.
🔬 Evidence snapshot
Overall evidence level here is listed as "Limited evidence". A detailed, source-reviewed evidence summary has not been completed yet.
🧪 Forms & quality
Needs evidence review — no source-reviewed information yet. We only show dose and monitoring details after they have been checked against reputable sources.
See the supplement glossary for what form names like "L-", chelated, or standardized extract mean.
📏 Dose & monitoring
Needs evidence review — no source-reviewed information yet. We only show dose and monitoring details after they have been checked against reputable sources.
Evidence vs. burden: Not yet reviewed
😐 Commonly reported side effects
- Uncommon at dietary levels; very high chronic intakes are associated with neurological discussions
Non-exhaustive and individual.
🔄 Cycling & breaks
No established cycling pattern.
📅 Daily use notes
Because most diets supply enough manganese, check whether your multivitamin already includes it before adding more.
📋 Source review status
Source-reviewed — last reviewed 2026-07-03
Reviewed against the NIH ODS manganese consumer fact sheet; editorial pass still pending.
Research backlog (queries to verify):
- manganese dietary adequacy supplementation need
- manganese excess neurological effects chronic high intake
📚 References
- NIH ODS — Manganese (Consumer Fact Sheet)NIH ODS — Full text reviewed 2026-07-03. Verified: adult UL 11 mg/day (all sources); excess associated with tremors, muscle spasms, hearing problems, mania, insomnia, depression; 'manganese is not known to interact or interfere with any medicines'; most diets supply enough.
Verified against the source shown. See the research-status page for how review works.
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