Vitamin E
Also known as: Alpha-tocopherol
Vitamin E is a fat-soluble antioxidant. Most people get enough from diet, and high-dose supplements are commonly discouraged because of possible bleeding risk and mixed outcome studies. It is fat-soluble, so it is taken with food.
Snapshot
What this page can tell you: Commonly discussed timing, food notes, caution categories, and an honest note on how much source review this entry still needs.
What it cannot: Whether this is appropriate for you personally, or that it treats, prevents, or cures any condition. Informational only — discuss with a clinician or pharmacist.
🕒 Timing
When: With a meal
Food: With a meal containing fat
Fat-soluble; commonly taken with a meal containing fat.
💊 Common use range
15 mg (≈22 IU)
Commonly cited adult upper limit around 1,000 mg/day of supplemental alpha-tocopherol; high doses may increase bleeding risk.
Ranges are informational, not a recommended dose. Talk to a professional about what is right for you.
🤔 Worth considering?
Evidence vs. effort: Mixed evidence relative to burden
Obtained easily from food; high-dose supplements are where the concerns are. High doses can increase bleeding risk and have a documented surgery and anticoagulant caution. Worth discussing with a professional before high-dose or perioperative use.
A general summary, not a recommendation. Whether something fits your situation is worth discussing with a healthcare professional.
⚠️ Commonly noted interactions (supplements)
None listed.
Often about absorption or timing rather than danger — separating doses is common. This list is not exhaustive.
🧭 Caution level
Ask a clinician or pharmacist before use.
- Bleeding / surgery caution category
- Commonly discussed upper limit
- Anticoagulant (blood thinner) interaction
- Antiplatelet interaction
Caution level is an informational summary of commonly discussed caution categories and doses — not a safety rating, approval, or medical advice. Low caution does not mean safe for you.
🩺 Medication caution categories
- Blood thinners (anticoagulants)
- Antiplatelet medication
🏥 Surgery & procedure caution
High-dose vitamin E may increase bleeding; commonly paused before surgery. Confirm with your care team.
If you have a procedure scheduled, bring your full supplement list to your surgical and anesthesia team. Do not stop prescribed medication unless your clinician tells you to. Do not start or stop supplements based only on this app.
✅ Quality checklist
- Prefer products with third-party testing or a certificate of analysis (COA).
- Check the label for the exact form and the elemental or active amount per serving.
🧩 Commonly paired with
🔁 Alternatives
None listed.
🗣️ Questions for a professional
- Is Vitamin E appropriate alongside my medications and health history?
- Is there a test or check that would tell us whether I actually need it?
🔬 Evidence snapshot
A fat-soluble antioxidant. Research on high-dose supplements for chronic disease is mixed and does not support routine high-dose use, which may carry risks.
🧪 Forms & quality
Needs evidence review — no source-reviewed information yet. We only show dose and monitoring details after they have been checked against reputable sources.
See the supplement glossary for what form names like "L-", chelated, or standardized extract mean.
📏 Dose & monitoring
NIH ODS sets an adult (19+) Tolerable Upper Intake Level of 1,000 mg/day of supplemental alpha-tocopherol (about 1,500 IU natural or 1,100 IU synthetic).
Evidence vs. burden: Mixed evidence relative to burden
😐 Commonly reported side effects
- Uncommon at dietary levels; bleeding risk at high doses
Non-exhaustive and individual.
🔄 Cycling & breaks
Not typically cycled.
📅 Daily use notes
Food-first is common; avoid stacking high-dose E from multiple products.
📋 Source review status
Source-reviewed — last reviewed 2026-07-02
Placeholder.
📚 References
- NIH ODS - Vitamin E (Health Professional Fact Sheet)NIH ODS — Verified UL, bleeding/hemorrhagic-stroke caution, and warfarin/antiplatelet and surgery interactions.
Verified against the source shown. See the research-status page for how review works.
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