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Semaglutide

Prescription medication

GLP-1 medication · also: ozempic, wegovy, rybelsus

An FDA-approved prescription GLP-1 medicine (brands Ozempic, Wegovy, Rybelsus) — a medication, not a supplement.

Not medical advice. SuppSafety and StackWise are informational only. Talk to a qualified healthcare professional before starting, stopping, or combining supplements.

People commonly track it for

Tracked as a prescription medicine (approved for type 2 diabetes, cardiovascular/kidney risk reduction, and chronic weight management) alongside a person's supplements.

Evidence summary

FDA-approved with established indications. Compounded or online 'versions' are not reviewed by the FDA the same way.

Regulation & source status

FDA-approved, prescription-only. The label carries a Boxed Warning tied to a thyroid-tumor finding in animal studies and is contraindicated with a personal/family history of medullary thyroid cancer or MEN 2 — only a clinician can determine whether it applies to you.

Route considerations

A subcutaneous injection (or, for Rybelsus, an oral tablet) used as prescribed. If you self-inject, safe sharps disposal is worth reviewing with a pharmacist.

Storage considerations

A cold-chain product — follow the label and your pharmacist's storage guidance; the FDA advises not using an injectable that arrived warm.

Interaction & context review

The label notes it slows gastric emptying, which can affect absorption of some oral medicines — whether the timing of any oral medicine needs attention is a question for your clinician or pharmacist. Don't start, stop, or change a prescription based on a tracker.

Sport / duty status

Not on the WADA Prohibited List as of the 2026 list; semaglutide is on WADA's Monitoring Program.

Track this item

Log it as a medication-context item to keep it with your supplements and export a clean list for your clinician. StackWise doesn't provide dosing or timing rules.

Track this itemPeptide safety & source review

Sources

Source reviewed: 2026-07-23.

Not medical advice. SuppSafety and StackWise are informational research and tracking tools. They are not medical advice and do not diagnose, treat, cure, or prevent any condition. Supplement research is often limited or mixed, and individual needs vary. Always talk to a qualified healthcare professional before starting, stopping, or combining supplements — especially if you take medication, have a health condition, are pregnant or breastfeeding, or have a procedure scheduled.