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TB-500 (thymosin β-4 fragment)

Research-use context

Research-use peptide · also: tb500, tb 500, thymosin beta-4 fragment, thymosin beta 4

A synthetic fragment related to thymosin β-4, sold as a research-use product; not FDA-approved.

Not medical advice. SuppSafety and StackWise are informational only. Talk to a qualified healthcare professional before starting, stopping, or combining supplements.

People commonly track it for

Most often logged in a soft-tissue recovery context — again, user intent, not a proven effect.

Evidence summary

Published human studies generally used full-length thymosin β-4; human data on the shorter TB-500 fragment specifically is very limited (the first registered fragment trial only began recruiting in 2026).

Regulation & source status

Not FDA-approved. Among the peptides under FDA compounding review as of July 2026 — under review is not approval.

Route considerations

Commonly discussed as an injectable in community settings. We don't provide route, preparation, or technique guidance — that's a clinician/pharmacist conversation.

Storage considerations

Often sold as a powder for reconstitution; unregulated products have no verified storage or stability data. Storage specifics belong to a pharmacist, not this profile.

Interaction & context review

Because human data is limited, interactions aren't well characterized. If you track it alongside other items or medications, review the full list with a clinician or pharmacist.

Sport / duty status

Prohibited in sport — WADA S2 covers thymosin-β4 and its derivatives such as TB-500.

Track this item

You can log this as a custom peptide / medication-context item — record your own source status, route, storage note, and a schedule, and include it in an export for your clinician. StackWise doesn't add a dose.

Track this itemPeptide safety & source review

Sources

Source reviewed: 2026-07-23.

Not medical advice. SuppSafety and StackWise are informational research and tracking tools. They are not medical advice and do not diagnose, treat, cure, or prevent any condition. Supplement research is often limited or mixed, and individual needs vary. Always talk to a qualified healthcare professional before starting, stopping, or combining supplements — especially if you take medication, have a health condition, are pregnant or breastfeeding, or have a procedure scheduled.